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שורה 1:
שורה 1: − <div style="direction:ltr"> − Dose Response Curve (DRC): − − When we give a dose of drug (DOG), − form 1 molecule up to any higher amount, − there is the Maximal Effect Dose (MED), − by means of treatment (changing a current state for a better one). − Thus, we also have dosages which are Non Maximal Effect Dosages (NMEDs). − − The ratio between any NMED to the MED, is called the Margin Of Safety (MOS). − There is an accepted formula to calculate MOS (to translate it to a dose). − MOS translated into a dosage is called a Terapheutic Index (TI). − To calculate TI, two different dosages are given to one group of examinees (in different, isolated periods). − The one which helps in at least 50% of the cases is the TI, the desired dosage. − − More dosage. − More risk. − Due to law of mass action. − − </div>
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